Genome-wide association study of antisocial personality disorder

The pathophysiology of antisocial personality disorder (ASPD) remains unclear. Although the most consistent biological finding is reduced grey matter volume in the frontal cortex, about 50% of the total liability to developing ASPD has been attributed to genetic factors. The contributing genes remain largely unknown. Therefore, we sought to study the genetic background of ASPD. We conducted a g...

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Antisocial Personality Disorder

Antisocial personality disorder (ASPD) is the most reliably diagnosed condition among the personality disorders, yet treatment efforts are notoriously difficult. Many psychiatrists are reluctant to treat patients with ASPD because of widespread belief that such patients are always untreatable. There is increasing evidence, however, that ASPD may, in certain cases, be treatable. In this chapter,...

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Treatment of antisocial personality disorder

Although Professor Maden’s article was only 100 words long, it contained some profound and, I think, unfair and unsubstantiated, statements. Where is the evidence that patients with severe antisocial personality disorders who do not want to be treated, like many of those detained in the dangerous and severe personality disorder (DSPD) unit at Broadmoor Hospital, where Professor Maden is the cli...

متن کامل

Treatment of antisocial personality disorder

Although Professor Maden’s article was only 100 words long, it contained some profound and, I think, unfair and unsubstantiated, statements. Where is the evidence that patients with severe antisocial personality disorders who do not want to be treated, like many of those detained in the dangerous and severe personality disorder (DSPD) unit at Broadmoor Hospital, where Professor Maden is the cli...

متن کامل

Treatment of antisocial personality disorder

Although Professor Maden’s article was only 100 words long, it contained some profound and, I think, unfair and unsubstantiated, statements. Where is the evidence that patients with severe antisocial personality disorders who do not want to be treated, like many of those detained in the dangerous and severe personality disorder (DSPD) unit at Broadmoor Hospital, where Professor Maden is the cli...

متن کامل

Genome-wide association study of antisocial personality disorder

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